Dostinex is a powerful and effective orally administered medicine, which is fundamentally designed for those women who are suffering from hyperprolactinemia or various diseased conditions created due to high prolactin level. Dostinex show its therapeutic actions due to its generic Cabergoline. It effectively overcomes the problems of high prolactin level and provides positive relief.


Prolactin is a natural polypeptide hormone, which is liberated by the pituitary gland and by the unusual actions of dopamine and its receptors. The liberation of prolactin totally depends on the actions of pituitary gland. Increased amount of prolactin in the human body is considered as hyperprolactinemia.


High prolactin levels may cause various disorders in men and women-

  • In men, it may induce infertility, erectile dysfunction, low sexual desire and gynecomastia.
  • In women, it may cause change in breast size, abnormal periods, abnormal secretion of breast milk and low sexual desire.


Pharmacological actions and doses of Dostinex-

Dostinex is an orally administered medication, which is primarily indicated to treat the symptoms of hyperprolactinemia or lower down the high level of prolactin hormone in the body. The increased level of prolactin causes unnecessary breast milk discharge, irregular periods and complexity in pregnancy time. Generic Cabergoline is a main therapeutic agent found in this drug and categorized under the class of long acting dopamine receptor agonist, which works by inhibiting the release of prolactin from the pituitary gland. Cabergoline binds on the D2 receptor, inhibiting the release of prolactin hormone from the pituitary gland.

Dostinex is found in the tablet dosage form and the initial recommended dosage of this medication is 0.25 mg twice a week and it can be easily increased after every 4 to 6 hours. It should be administered orally with a full glass of water. Dostinex therapy should be continued for 6months with or without food. Do not take two pills of Dostinex at a time as it may induce overdose of this drug and severe undesirable complications.


Female with hypersensitivity to ergot derivatives, severe cardiovascular disease, high blood pressure, gastro duodenal ulcers, Reynaud's disease, blood related disorders like anemia, leukemia and sickle cell anemia, liver problem and renal impairment should not take this drug without consulting doctor.


While taking this medicine, a female may suffer several adverse effects like Depression, cramps, muscle pain, stomach pain, nervousness, breast pain, skin itching, indigestion, joint pain, muscle stiffness and sleep disturbances.


Safety measures should be adopted while taking Dostinex-

  • Dostinex should not be taken along with alcohol as it may increase adverse effects.
  • Breast feeding mothers should strictly avoid Dostinex.
  • Children below the age of 17 years should not take this medicine.
  • Avoid driving or any work, which needs attentiveness as this drug may affect your ability to drive and make you drowsy.  
  • Macrolide antibiotic should be strictly inadvisable along with this drug as it may cause severe harmful health complications.


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