Iressa treats non-small cell lung cancer (NSCLC) where lung tissues develop malignancy. It has Generic Gefitinib as its main active component. Also available as brand Gefticip, its function is to inhibit a protein called Epidermal Growth Factor Receptor (EGFR), which aids in the growth and multiplication of malignant cells.

A drug with a targeted approach, Iressa is contraindicated in some conditions. Patients with a history of hypersensitivity to Gefitinib or any other excipients cannot risk using this medication. It is contraindicated in people who have a history of breathing problems or any other respiratory issues or diseases. It is too strong a medication to be ingested by pregnant women and breast-feeding mothers and is contraindicated for this group. This medication cannot be administered to people with renal and liver disorders

Concomitant treatment with the following drugs may inhibit Iressa’s function or bring-on adverse reactions in patients: Anticonvulsants like Phenytoin or Carbamazepine; Antifungals like Fluconazole; Sedatives; Blood thinners like Warfarin; Tuberculosis drugs like Rifampicin; Medications and remedies composed of St John’s wort.

Storage, dosage, usage and precautions:

Ideally Iressa must be stored at room temperature, in a cool and dry place away from children.

Gefticip (Iressa) comes as a 250 mg tablet oral formulation, to be had one per day. The tablet is ingested at approximately the same time every day, either as a whole with water or as a swirled dispersion (without crushing the tablet), with or without food.

If a dose is missed, it could be administered when the patient remembers, but if there is less than 12 hours for the next dose, the patient should just skip the missed dose and take the next one on time. Never should a double dose be taken to make up for a missed dose.

The only way to deal with an overdose is to contact the nearest medical establishment immediately.

Some of the common side effects associated with the administration of Iressa (Gefticip) are Anorexia mild or moderate, severe stomach pain, diarrhea, vomiting, nausea, weakness, watery eyes, eye pain or redness, skin reactions such as rash, which is sometimes itchy, dry, red or sore mouth and nail disorders.

Precautionary measures:

  • Avoid the use of Iressa if you already suffer from vision problems.
  • Iressa adds lactose to the body as it contains lactose. People with past or current Lactose intolerance must not take this medicine without consulting their doctor.
  • There is no data to indicate that this drug hampers your ability to focus or perform any heavy physical tasks. However, some people may feel signs of weakness after consuming Iressa and they must give take due care while deciding to drive or take on physically taxing work.


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