Comptoser is a semi-synthetic analog in chemical terms of the natural alkaloid Camptothecin. Irinotecan is the active drug in Comptoser used for the treatment of Metastatic colon or rectal cancer. Comptoser is an FDA approved drug.


 Cancer is a malignant growth or tumor resulting from an uncontrolled division of cells.

  • Breast cancer (cancer that forms in the cells of the breasts).
  • Prostate cancer (cancer in a man's prostate, a small walnut-shaped gland that produces seminal fluid).
  • Basal cell cancer (A type of skin cancer that begins in the basal cells).
  • Melanoma (The most serious type of skin cancer).
  • Colon cancer (A cancer of the colon or rectum, located at the lower end of the digestive tract).
  • Lung cancer (cancer that begins in the lungs and most often occurs in people who smoke).
  • Leukemia (A cancer of blood-forming tissues, hindering the body's ability to fight against infection).
  • Lymphoma (A cancer of the lymphatic system).
  • Rectal cancer (malignant cancer cells form in the tissues of the rectum).


Comptoser is the best drug used in the treatment of rectal cancer.


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 Comptoser is a camptothecin derivative. It act by interacting with topoisomerase I enzyme.   And releves the torsional strain in DNA by leading reversible single-strand breaks.


Comptoser for Rectal cancer


What are the dosage instructions for COMPTOSER (IV)?

Comptoser is given by infusion through intravenous route. It is to be taken by patients as prescribed.

Comptoser is available in different dosages 2 mL, 5 mL and 15 ml vials.


When should you not use this medication?


Comptoser Injection is contraindicated in patients who are hypersensitive to the drug or its excipients.


What are the adverse effects observed while using this medication?


Common side effects of Comptoser include nausea, vomiting, loss of appetite, constipation, cough, drowsiness, trouble sleeping, dizziness skin rash, or redness or peeling of the skin on your hands and feet. Temporary hair loss may occur.


What are the safety measures you should follow while taking COMPTOSER?


  • Share your complete medical history with your doctor before starting Comptoser treatment.
  • Inform your health care professional if you are pregnant.
  • If you have redness or pain at the infusion site apply ice and inform your doctor.
  • Do not conceive a child (get pregnant) while taking Comptoser.
  • Drink at least two to three quarts of fluid every 24 hours.
  • Do not breast-feed while taking Comptoser.


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