Altamofen - tamoxifen

Altamofen - tamoxifen

Altamofen-tamoxifen

Availability: In stock

$0.73

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Quantity Strength Unit Price Price Cart
50 tablets Altamofen 20 Tablets $1.03 $51.30
100 tablets Altamofen 20 Tablets $0.83 $82.60
150 Tablets Altamofen 20 Tablets $0.73 $108.90

Details

Altamofen contains Tamoxifen as an active ingredient. It is a non-steroidal antioestrogenic drug for oral administration. This medication is indicated for the treatment of advanced breast cancer and adjuvant treatment of early breast cancer. It can also be used as an alternative to oophorectomy or ovarian irradiation.

Mechanism of action of Altamofen-

Altamofen with an active ingredient Tamoxifen is a nonsteroidal agent that binds to estrogen receptors (ER), inducing a conformational change in the receptor. It may lead to a blockage or change in the expression of estrogen dependent genes. The prolonged binding of Tamoxifen to the nuclear chromatin of these results in reduced DNA polymerase activity, impaired thymidine utilization, blockade of estradiol uptake, and decreased estrogen response. It is likely that Tamoxifen interacts with other co activators or co repressors in the tissue and binds with different estrogen receptors, ER-alpha or ER-beta, producing both estrogenic and antiestrogenic effects.

Dosage Information for Altamofen-

Altamofen is available as 20mg tablets to be taken orally twice a day with plenty amount of water. This medication should be taken only after the prescription from the doctor. Do not crush or chew the tablet; swallow the tablet as a whole. However, some side effects are likely to occur while using this medication such as headache, fever, nausea, vomiting, edema, hair loss, vaginal bleeding etc.

Contraindications-

  • Avoid using the medication in case of any allergic reactions to the active ingredient
  • Contraindicated in infants, children, pregnant women and lactating mothers

Drug Interactions-

  • This medication potentiates the anticoagulant effect of Warfarin.
  • It may increase the risk of thromboembolism when used in combination with cytotoxic agents.
  • Use of Rifampicin or Aminogluthemide with Altamofen reduces the plasma concentration.

Storage Conditions-

This medication is to be stored at room temperature; to be kept away from heat, sunlight and moisture. Keep it away from children and pets.

Precautionary measures-

  • Avoid engaging in any activity that require your alertness as this medication causes drowsiness
  • This medication can cause sensitivity reactions, so avoid going in sun.

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